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The undifferentiated nucleotide specificities of certain archaeal ligases have tantalizing implications for enzyme evolution as well as doable use of ADP as a substrate by ancestors of modern DNA ligases. The power of some archaeal ligases to use ATP and NAD+ or ATP and ADP as substrates may be explained when they identified just the ADP component typical to all a few nucleotides.
The motion involves a rigid entire body rotation with regards to the hinge section connecting the NTase and OB domains (indicated by the arrow
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El primer gran anuncio del Embajador para la Liga II fue la contratación de Falcao García quien jugará por primera vez en el fileútbol profesional colombiano tras su largo paso por las mejores ligas del mundo.
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